Can One Build A Tolerance To CBD?

Many experts advise starting slowly while starting your CBD journey. This implies that you should begin with CBD in smaller doses before moving on to higher choices. You could, however, worry if this implies that you can eventually develop a tolerance to CBD.

We at Holistic Hemp Scotland are aware that you might have inquiries. We’ve all been there, in actuality. After all, most supplements can cause you to develop a tolerance to them. What makes CBD any different, then?

We’re answering any queries you might have today regarding CBD and tolerance.

What Does Tolerance To CBD Mean?

Tolerance in this context refers to developing a tolerance to a substance. As a result, you might need to take a higher dose to get the same results. In many instances, the same amount just won’t have the same effects over time.

Medicine or dietary supplements are frequently closely linked to intolerance. Tolerance can also develop to other chemicals, such as caffeine and spicy foods. People with allergies may even be able to develop a tolerance to their allergies by working with an allergist.

Because of our bodies, we develop a tolerance to outside toxins. This is due to the fact that our bodies constantly strive to maintain equilibrium. In order to maintain homeostasis, a foreign substance must be successfully neutralised by our bodies.

Because our bodies absorb these compounds and successfully neutralise them, we develop a tolerance to certain substances. Our bodies become accustomed to certain toxins over time and can neutralise them more quickly. This indicates that we must ingest higher amounts of a material until our bodies neutralise that as well in order to receive the same effects.

Can I Develop A Tolerance To Cannabinoids?

You can, indeed. You can build up a tolerance to some cannabinoids in your body just like you can to anything else. One of these cannabinoids is THC.

Therefore, if you use THC on a frequent basis, your body can gradually develop a tolerance to it. As a result, you might eventually need to take higher amounts of THC. Over time, this can also make the THC useless.

But does the same hold true for CBD if THC tolerance may also be built up? We’ll tell you, though.

What About Tolerance To CBD?

Because CBD interacts differently with your CB1 receptors than THC does, research shows that you cannot become used to it. This indicates that if you find the ideal CBD dosage, you may probably remain with it for a while. Your CBD dosage, however, may vary based on a variety of physical factors.

For instance, you might need to reduce your dose if you lose a lot of weight. You can also gradually start to reduce your dose as you age. Indeed, when CBD builds up in your system over time, experts hypothesise that long-term CBD use could lead to reverse tolerance.

This is due to the ability of CBD to raise endocannabinoid levels. As a result, regular CBD use may result in permanently elevated endocannabinoid levels. This implies that you might require reduced amounts of CBD over time.

It’s crucial to keep in mind, though, that the concept of reverse CBD tolerance is just that—a theory. While additional research may support these assertions, researchers are still closely examining CBD and our endocannabinoid system. Their study suggests that you cannot actually develop a tolerance to CBD.

Therefore, do not worry! Without worrying about developing a tolerance to CBD, you can keep taking your regular dose.

So, What Makes THC Different?

We already warned that regular THC users may develop a tolerance to the compound. What distinguishes THC from CBD if they are both cannabinoids? Again, your endocannabinoid system (ECS) and CB1 receptors are responsible for everything.

The brain’s CB1 receptors are frequently binders of THC, which causes psychoactive effects. Low amounts of THC may initially be effective, but continued use may lead to a reduction in cannabinoid receptors. This occurs when your body tries to control THC doses that are given frequently or all at once in significant amounts.

Because there are fewer cannabinoid receptors, more THC is required to fully experience its effects. However, this could cause paranoia, sleeplessness, and hallucinations. Furthermore, THC is regarded as a prohibited substance in the UK and Ireland. As a result, even full-spectrum CBD only includes minute levels of THC, we advise sticking to CBD.

Why Doesn’t My CBD Product Seem To Work?

Tolerance to CBD was previously considered as being extremely improbable. In actuality, the majority of CBD products have zero-tolerance builds since they have high CBD content and very little THC. However, occasionally your CBD product may not perform as effectively as you would like. There may be a variety of causes for this.

Your CBD product may first be outdated. Perhaps you purchased CBD tincture in large quantities but only sometimes used it. Even though there may not be any obvious evidence of deterioration, potency might deteriorate over time.

We advise getting your CBD from a trustworthy supplier for the greatest outcomes. Watch out for producers who use a lab for independent testing, such as Holistic Hemp Scotland. Read through their third-party test results before making a purchase to be sure you’re getting a quality product with the right dosage of CBD.

There Could Also Be CBD Build-Up

In addition to these factors, buildup in your system could make your preferred CBD product less effective. This should not be confused with CBD tolerance; CBD has accumulated in your body rather than engaging with your CB1 receptors. As a result, there is a kind of backlog created, which implies that the benefits may not be felt right away.

When you continuously use the same product, this may occur. It may also occur if you take a bigger amount of CBD than is necessary or too much CBD. Thankfully, there are simple, workable solutions for this.

Hold off on the CBD if you want to fix this. Take into account a little vacation from CBD products. For the majority of people, a 48-hour gap should be sufficient to reset your system and remove the CBD backlog from it.

There is a solution, though, if you don’t want to temporarily stop using CBD. Simply switch to a different type that contains a lower concentration of CBD in this situation. Consider switching, for a few days, to CBD edibles. On the other hand, if you typically use edibles, think about switching to an alternative form, such as sublingual tincture or an oral spray.

It’s advised to wait up to five days after using one of these techniques before returning to your chosen CBD product. But keep in mind that you’re beginning from scratch because you’ve reset your system virtually. As a result, it’s advised to start with smaller doses of CBD before increasing it to your usual level.

Tolerance To CBD: Key Takeaways

Do you therefore develop a tolerance to CBD? The quick response is no. This indicates that, unless you suffer significant physical changes, you can use the same CBD dose repeatedly.

For instance, a decline in metabolic rate, drastic weight loss or growth, and ageing may indicate that you need to reconsider your CBD intake. As a result, it’s crucial to periodically assess your CBD intake. You might be consuming too much or not enough CBD, after all.

Additionally, keep in mind that CBD can accumulate in your body. This does not, however, imply that you have become accustomed to it. It is also simply fixable; in this case, a brief break from CBD should work! Alternately, try a lesser dose of a different CBD product for a few days.

By doing this, you should be able to remove the buildup and resume using your preferred product. However, if it doesn’t work, you might be utilising a subpar product. No matter what kind of CBD product you want, it’s crucial to get it from a reliable supplier and to review the Certificates of Analysis before buying.

We at Holistic Hemp Scotland obtain our products from some of the top producers in the industry. To assure superior quality in every batch, these goods are thoroughly tested before shipping. Why not glance through our product selection right now if you’re looking for a new CBD product?


Fernandez, S. (2021) Can you build a tolerance to CBD?, CBD Village UK. Available at: (Accessed: December 26, 2022).

About the author : Alex Sikorsky